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[Rapid determination of 8 urinary carbamate pesticides by liquid chromatography-tandem mass spectrometry].
- Source :
-
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases [Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi] 2015 Nov; Vol. 33 (11), pp. 857-9. - Publication Year :
- 2015
-
Abstract
- Objective: To establish a method for simultaneously determining the urinary concentrations of 8 carbamate pesticides.<br />Methods: After being purified by acetonitrile precipitation, urine samples were transferred to a liquid chromatography-tandem mass spectrometry system, and the concentrations of 8 carbamate pesticides were determined by external standard method. A C18 column was used for ultra-high-performance liquid chromatography; methanol/ammonium acetate solution was used as the mobile phase for gradient elution; the mass spectrometer was operated in a multi-reaction monitoring mode.<br />Results: The calibration curves were linear when the urinary concentrations of these carbamate pesticides were 20~800 µg/L, and the recovery rates were 61.0%~121% at spiked levels of 20, 200 and 800 µg/L, with a relative standard deviation of 1.7%~5.5%.<br />Conclusion: This determination method meets the Guide for establishing occupational health standards-part 5: Determination methods of chemicals in biological materials, and can be used for simultaneous determination of 8 carbamate pesticides in the urine of poisoning patients.
Details
- Language :
- Chinese
- ISSN :
- 1001-9391
- Volume :
- 33
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases
- Publication Type :
- Academic Journal
- Accession number :
- 26887277