Graphene oxide for rapid determination of testosterone in the presence of cetyltrimethylammonium bromide in urine and blood plasma of athletes.

Authors :: Heidarimoghadam R
Akhavan O
Ghaderi E
Hashemi E
Mortazavi SS
Farmany A
Source :: Materials science & engineering. C, Materials for biological applications [Mater Sci Eng C Mater Biol Appl] 2016 Apr 01; Vol. 61, pp. 246-50. Date of Electronic Publication: 2015 Dec 04.
Publication Year :: 2016
Abstract: Electro-reduction behavior of testosterone at reduced graphene oxide/glassy carbon electrode (rGO/GCE) was studied. Cationic surfactant cetyltrimethylammonium bromide (CTAB) enhanced the reduction peak of testosterone. In borate buffer (pH5.4) CTAB-testosterone showed a reduction peak at -1.1 V (versus, Ag/AgCl). The increment of peak current obtained by deducting the reduction peak current of the CTAB-testosterone was rectilinear with testosterone concentration in the range of 2.0 to 210.0 nM, with a detection limit of 0.1 nM. The sensor was used for quantification of testosterone in biological fluids and drug.<br /> (Copyright © 2015 Elsevier B.V. All rights reserved.)

Subjects :: Cetrimonium
Female
Humans
Male
Sensitivity and Specificity
Athletes
Cetrimonium Compounds chemistry
Graphite chemistry
Testosterone blood
Testosterone urine

Language :: English
ISSN :: 1873-0191
Volume :: 61
Database :: MEDLINE
Journal :: Materials science & engineering. C, Materials for biological applications
Publication Type :: Academic Journal
Accession number :: 26838847
Full Text :: https://doi.org/10.1016/j.msec.2015.12.005

Full Text Access

Tools