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Nanopore Sequencing as a Rapidly Deployable Ebola Outbreak Tool.

Authors :
Hoenen T
Groseth A
Rosenke K
Fischer RJ
Hoenen A
Judson SD
Martellaro C
Falzarano D
Marzi A
Squires RB
Wollenberg KR
de Wit E
Prescott J
Safronetz D
van Doremalen N
Bushmaker T
Feldmann F
McNally K
Bolay FK
Fields B
Sealy T
Rayfield M
Nichol ST
Zoon KC
Massaquoi M
Munster VJ
Feldmann H
Source :
Emerging infectious diseases [Emerg Infect Dis] 2016 Feb; Vol. 22 (2), pp. 331-4.
Publication Year :
2016

Abstract

Rapid sequencing of RNA/DNA from pathogen samples obtained during disease outbreaks provides critical scientific and public health information. However, challenges exist for exporting samples to laboratories or establishing conventional sequencers in remote outbreak regions. We successfully used a novel, pocket-sized nanopore sequencer at a field diagnostic laboratory in Liberia during the current Ebola virus outbreak.

Details

Language :
English
ISSN :
1080-6059
Volume :
22
Issue :
2
Database :
MEDLINE
Journal :
Emerging infectious diseases
Publication Type :
Academic Journal
Accession number :
26812583
Full Text :
https://doi.org/10.3201/eid2202.151796