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[Total Pelvic Exenteration for Local Recurrence of Rectal Cancer Appearing 12 Years after Curative Operation--A Case Report].
- Source :
-
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2015 Nov; Vol. 42 (12), pp. 2337-9. - Publication Year :
- 2015
-
Abstract
- A 49-year-old man had undergone Hartmann's operation for rectal cancer in August 2002. The disease stage (TNM 7th) was T3, N1, M0, Stage ⅢB. He was treated with UFT and Krestin for a year as adjuvant chemotherapy. No recurrence had been detected after the surgery. In July 2014, he presented with symptoms of acute renal failure. A CT scan showed bilateral hydronephrosis and a pelvic tumor between the urinary bladder and rectum. The pathological diagnosis based on biopsy specimens was adenocarcinoma. Because immunostaining studies of the tumor biopsy specimen revealed that CK20, CEA, CA19-9, and p53 were positive and CK7 and PSA were negative, this pelvic tumor was diagnosed as a local recurrence of rectal cancer. Total pelvic exenteration and ileal conduit urinary diversion were carried out for the recurrent tumor with curative intent. The reported recurrence rate of Stage Ⅲ colorectal cancer 5 years after the initial curative operation is 0.67%. Local recurrence of rectal cancer 12 years after the initial operation is quite rare. Immunostaining is helpful to discriminate between rectal cancer and a tumor of the urinary organs. It is important to consider that recurrence of rectal cancer might still occur a long time after the initial operation.
- Subjects :
- Chemotherapy, Adjuvant
Humans
Male
Middle Aged
Pelvic Exenteration
Pelvic Neoplasms secondary
Rectal Neoplasms complications
Rectal Neoplasms drug therapy
Rectal Neoplasms surgery
Recurrence
Time Factors
Treatment Outcome
Adenocarcinoma complications
Adenocarcinoma drug therapy
Adenocarcinoma secondary
Adenocarcinoma surgery
Pelvic Neoplasms surgery
Rectal Neoplasms pathology
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0385-0684
- Volume :
- 42
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Gan to kagaku ryoho. Cancer & chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 26805356