[Assessment of tolerability and antihypertensive efficacy of aceplus mite (captopril (CPT) 50 mg + hydrochlorothiazide (HCTZ) 15 mg): a double-blind study vs. HCTZ in diabetic hypertensive patients. A report on three treatments].

Thirty hypertensive diabetic patients were randomly, double blindly, treated with Captopril (CPT) 50 mg + hydrochlorothiazide (HCTZ) 15 mg (No 19) or HCTZ 25 mg alone (No 11) for 3 months, to assess blood pressure control and some metabolic modifications. The results indicate that CPT + a low dose of HCTZ maintains the synergistic effect of the two drugs, minimizing the metabolic problems related to HCTZ in hypertensive diabetic patients.