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Infection with human T-lymphotropic virus types-1 and -2 (HTLV-1 and -2): Implications for blood transfusion safety.
- Source :
-
Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine [Transfus Clin Biol] 2016 Feb; Vol. 23 (1), pp. 13-9. Date of Electronic Publication: 2016 Jan 05. - Publication Year :
- 2016
-
Abstract
- Many countries currently perform antibody screening for HTLV-1 infection in blood donors, and this intervention is likely cost-effective in preventing HTLV-1 related diseases in high prevalence countries. However, a number of high-income countries with low prevalence of HTLV-1 infection also perform universal HTLV-1 screening and debate has arisen regarding the cost-effectiveness of these strategies. Filter-based leukoreduction is likely to substantially reduce HTLV-1 transmission by removing infected lymphocytes, but actual laboratory data on its efficacy is currently lacking. Similarly, cost-effectiveness research on HTLV-1 prevention strategies is limited by poor data on prevalence, transmission efficacy and the cost of treating HTLV1 diseases.<br />Competing Interests: of interest The author declares that he has no competing interest.<br /> (Copyright © 2016 Elsevier Masson SAS. All rights reserved.)
- Subjects :
- Blood Donors
Blood Safety
Blood Transfusion standards
Cost-Benefit Analysis
Forecasting
Global Health
HTLV-I Infections epidemiology
HTLV-I Infections prevention & control
HTLV-I Infections transmission
HTLV-II Infections epidemiology
HTLV-II Infections prevention & control
HTLV-II Infections transmission
Humans
Leukocyte Reduction Procedures
Lymphocytes virology
Prevalence
Seroconversion
Transfusion Reaction
Viremia epidemiology
Viremia transmission
Donor Selection economics
Donor Selection standards
HTLV-I Infections blood
HTLV-II Infections blood
Human T-lymphotropic virus 1 isolation & purification
Human T-lymphotropic virus 2 isolation & purification
Viremia diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1953-8022
- Volume :
- 23
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine
- Publication Type :
- Academic Journal
- Accession number :
- 26778839
- Full Text :
- https://doi.org/10.1016/j.tracli.2015.12.001