Infection with human T-lymphotropic virus types-1 and -2 (HTLV-1 and -2): Implications for blood transfusion safety.

Authors :: Murphy EL
Source :: Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine [Transfus Clin Biol] 2016 Feb; Vol. 23 (1), pp. 13-9. Date of Electronic Publication: 2016 Jan 05.
Publication Year :: 2016
Abstract: Many countries currently perform antibody screening for HTLV-1 infection in blood donors, and this intervention is likely cost-effective in preventing HTLV-1 related diseases in high prevalence countries. However, a number of high-income countries with low prevalence of HTLV-1 infection also perform universal HTLV-1 screening and debate has arisen regarding the cost-effectiveness of these strategies. Filter-based leukoreduction is likely to substantially reduce HTLV-1 transmission by removing infected lymphocytes, but actual laboratory data on its efficacy is currently lacking. Similarly, cost-effectiveness research on HTLV-1 prevention strategies is limited by poor data on prevalence, transmission efficacy and the cost of treating HTLV1 diseases.<br />Competing Interests: of interest The author declares that he has no competing interest.<br /> (Copyright © 2016 Elsevier Masson SAS. All rights reserved.)

Language :: English
ISSN :: 1953-8022
Volume :: 23
Issue :: 1
Database :: MEDLINE
Journal :: Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine
Publication Type :: Academic Journal
Accession number :: 26778839
Full Text :: https://doi.org/10.1016/j.tracli.2015.12.001

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