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Infectious Spondylitis in a Patient with Chronic Kidney Disease: Identification of Campylobacter fetus Subsp. testudinum by 16S Ribosomal RNA Sequencing.

Authors :
Choi HS
Shin SU
Bae EH
Ma SK
Kim SW
Source :
Japanese journal of infectious diseases [Jpn J Infect Dis] 2016 Nov 22; Vol. 69 (6), pp. 517-519. Date of Electronic Publication: 2016 Jan 08.
Publication Year :
2016

Abstract

We report the first case of spondylitis with bacteremia caused by Campylobacter fetus subsp. testudinum identified by 16S ribosomal ribonucleic acid (rRNA) gene sequencing. An 81-year-old man presented with fever and general weakness. His medical history included end-stage renal disease, hypertension, and type 2 diabetes. Despite empirical antibiotic treatment, his fever and back pain persisted. Magnetic resonance imaging with gadolinium enhancement showed a low-signal-intensity lesion in T1-weighted imaging and a high-signal-intensity lesion in T2-weighted imaging at the L3 vertebral body. C. fetus grew on 1 pair of blood cultures. C. fetus subsp. testudinum was identified via 16S rRNA sequencing of the cultivated organisms. The patient recovered uneventfully after 6 weeks of optimal antibiotic treatment, selected using susceptibility tests. C. fetus spondylitis is a very rare disease. In this unique case involving end-stage renal disease, the underlying pathogen was identified by 16S rRNA sequencing.

Details

Language :
English
ISSN :
1884-2836
Volume :
69
Issue :
6
Database :
MEDLINE
Journal :
Japanese journal of infectious diseases
Publication Type :
Academic Journal
Accession number :
26743148
Full Text :
https://doi.org/10.7883/yoken.JJID.2015.461