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Tribological efficacy and stability of phospholipid-based membrane lubricants in varying pH chemical conditions.
- Source :
-
Biointerphases [Biointerphases] 2016 Mar 04; Vol. 11 (1), pp. 019002. Date of Electronic Publication: 2016 Mar 04. - Publication Year :
- 2016
-
Abstract
- In this study, the authors examine the influence of joint chemical environment by measuring changes in the tribological properties (friction coefficient and charge density) of contacting surfaces of normal and degenerated cartilage samples in bath solutions of varying pH (2.0-9.0). Bovine articular cartilage samples (nā=ā54) were subjected to several surface measurements, including interfacial energy, contact angle, and friction coefficient, at varying pH. The samples were delipidized and then subjected to the same measurement protocols. Our results reveal that the interfacial energy and charge density, which have been shown to be related to friction coefficient, decrease with pH in the acidic range and approach constant values at physiological (or synovial fluid) pH of 7.4 and beyond it, i.e., toward basic pH domain. The authors conclude that this rather complex response explains the long-term efficacy with respect to ageing and associated pH changes, of the phospholipid layers that facilitate the almost frictionless, hydration-lubrication involving contact in the mammalian musculoskeletal system.
Details
- Language :
- English
- ISSN :
- 1559-4106
- Volume :
- 11
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Biointerphases
- Publication Type :
- Academic Journal
- Accession number :
- 26727914
- Full Text :
- https://doi.org/10.1116/1.4939246