OfftargetFinder: a web tool for species-specific RNAi design.

Authors :: Good RT
Varghese T
Golz JF
Russell DA
Papanicolaou A
Edwards O
Robin C
Source :: Bioinformatics (Oxford, England) [Bioinformatics] 2016 Apr 15; Vol. 32 (8), pp. 1232-4. Date of Electronic Publication: 2015 Dec 24.
Publication Year :: 2016
Abstract: Motivation: RNA interference (RNAi) technology is being developed as a weapon for pest insect control. To maximize the specificity that such an approach affords we have developed a bioinformatic web tool that searches the ever-growing arthropod transcriptome databases so that pest-specific RNAi sequences can be identified. This will help technology developers finesse the design of RNAi sequences and suggests which non-target species should be assessed in the risk assessment process.<br />Availability and Implementation: http://rnai.specifly.org<br />Contact: crobin@unimelb.edu.au.<br /> (© The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.)