[Isolation and properties of hybridomas producing monoclonal antibodies to the Leningrad-16 measles virus].

A panel of 18 hybridomas producing MCA to measles virus (the L-16 strain) was produced by somatic hybridization method. Thirteen hybridomas produce immunoglobulins of the G class represented by all known subclasses of mouse immunoglobulins; the subclass G 2a is predominant. Five hybridomas produce immunoglobulins of the M class. The resulting preparations of MCA are highly reactive in several serological tests: IFA, NIF, HI, NT. MCA have been divided into 3 groups according to their capacity to combine with three strains of morbilli viruses: L-16, LEC, and carnivora distemper virus (strain EPM).