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The stereoselective construction of E- and Z-Δ-Ile from E-dehydroamino acid ester: the synthesis of the phomopsin A tripeptide side chain.

Authors :
Yasuno Y
Nishimura A
Yasukawa Y
Karita Y
Ohfune Y
Shinada T
Source :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2016 Jan 25; Vol. 52 (7), pp. 1478-81. Date of Electronic Publication: 2015 Dec 10.
Publication Year :
2016

Abstract

The stereoselective synthesis of the phomopsin A tripeptide side chain was achieved by using methyl 2-(((benzyloxy)carbonyl)amino)-2-(diphenoxyphosphoryl)acetate as a common synthetic precursor for the synthesis of E-Δ-dehydroisoleucine and E-Δ-aspartate.

Details

Language :
English
ISSN :
1364-548X
Volume :
52
Issue :
7
Database :
MEDLINE
Journal :
Chemical communications (Cambridge, England)
Publication Type :
Academic Journal
Accession number :
26658962
Full Text :
https://doi.org/10.1039/c5cc08458j