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Review: circulating tumor cells in the practice of breast cancer oncology.
- Source :
-
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2016 Aug; Vol. 18 (8), pp. 749-59. Date of Electronic Publication: 2015 Dec 08. - Publication Year :
- 2016
-
Abstract
- The primary cause of tumor-related death in breast cancer is still represented by distant metastasization. The dissemination of tumor cells from the primary tumor to distant sites through bloodstream cannot be early detected by standard imaging methods. Circulating tumor cells (CTCs) play a major role in the metastatic spread of breast cancer. Different analytical systems for CTCs isolation and detection have been developed and novel areas of research are directed towards developing assays for CTCs molecular characterization. This review describes the current state of art on CTCs detection techniques and the present and future clinical implications of CTCs enumeration and characterization.
Details
- Language :
- English
- ISSN :
- 1699-3055
- Volume :
- 18
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
- Publication Type :
- Academic Journal
- Accession number :
- 26646763
- Full Text :
- https://doi.org/10.1007/s12094-015-1460-2