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Chlorpyrifos chronic toxicity in broilers and effect of vitamin C.
- Source :
-
Open veterinary journal [Open Vet J] 2011; Vol. 1 (1), pp. 21-7. Date of Electronic Publication: 2011 Feb 25. - Publication Year :
- 2011
-
Abstract
- An experiment was conducted to study chlorpyrifos chronic toxicity in broilers and the protective effect of vitamin C. Oral administration of 0.8 mg/kg body weight (bw) (1/50 LD50) chlorpyrifos (Radar(®)), produced mild diarrhea and gross lesions comprised of paleness, flaccid consistency and slightly enlargement of liver. Histopathologically, chlorpyrifos produced degenerative changes in various organs. Oral administration of 100 mg/kg bw vitamin C partially ameliorated the degenerative changes in kidney and heart. There was insignificant alteration in biochemical and haematological profiles. It is concluded that supplementation of vitamin C reduced the severity of lesions induced by chronic chlorpyrifos toxicity in broilers.
Details
- Language :
- English
- ISSN :
- 2226-4485
- Volume :
- 1
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Open veterinary journal
- Publication Type :
- Academic Journal
- Accession number :
- 26623275