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Vancomycin Dosing Practices, Trough Concentrations, and Predicted Area Under the Curve in Children With Suspected Invasive Staphylococcal Infections.

Authors :
Chhim RF
Arnold SR
Lee KR
Source :
Journal of the Pediatric Infectious Diseases Society [J Pediatric Infect Dis Soc] 2013 Sep; Vol. 2 (3), pp. 259-62. Date of Electronic Publication: 2012 Sep 11.
Publication Year :
2013

Abstract

Recent guidelines recommend empiric vancomycin dosing of 60 mg/kg per day and consideration of higher trough concentrations (15-20 mcg/mL) in children with invasive infections. In this study, we report a retrospective review evaluating the dose/trough relationship and predicted area under the curve in pediatric patients receiving vancomycin for invasive staphylococcal infections.<br /> (© The Author 2012. Published by Oxford University Press on behalf of the Pediatric Infectious Diseases Society. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.)

Details

Language :
English
ISSN :
2048-7193
Volume :
2
Issue :
3
Database :
MEDLINE
Journal :
Journal of the Pediatric Infectious Diseases Society
Publication Type :
Academic Journal
Accession number :
26619480
Full Text :
https://doi.org/10.1093/jpids/pis083