Chitosan as a starting material for wound healing applications.

Authors :: Patrulea V
Ostafe V
Borchard G
Jordan O
Source :: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2015 Nov; Vol. 97 (Pt B), pp. 417-26.
Publication Year :: 2015
Abstract: Chitosan and its derivatives have attracted great attention due to their properties beneficial for application to wound healing. The main focus of the present review is to summarize studies involving chitosan and its derivatives, especially N,N,N-trimethyl-chitosan (TMC), N,O-carboxymethyl-chitosan (CMC) and O-carboxymethyl-N,N,N-trimethyl-chitosan (CMTMC), used to accelerate wound healing. Moreover, formulation strategies for chitosan and its derivatives, as well as their in vitro, in vivo and clinical applications in wound healing are described.<br /> (Copyright © 2015 Elsevier B.V. All rights reserved.)

Subjects :: Animals
Bandages
Chemistry, Pharmaceutical
Chitosan administration & dosage
Chitosan analogs & derivatives
Chitosan toxicity
Humans
Hydrogels
Chitosan pharmacology
Wound Healing drug effects

Language :: English
ISSN :: 1873-3441
Volume :: 97
Issue :: Pt B
Database :: MEDLINE
Journal :: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
Publication Type :: Academic Journal
Accession number :: 26614560
Full Text :: https://doi.org/10.1016/j.ejpb.2015.08.004