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Quantitative multi-slice computed tomography assessment of the mitral valvular complex for transcatheter mitral valve interventions part 1: systematic measurement methodology and inter-observer variability.
- Source :
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EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology [EuroIntervention] 2016 Oct 10; Vol. 12 (8), pp. e1011-e1020. Date of Electronic Publication: 2016 Oct 10. - Publication Year :
- 2016
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Abstract
- Aims: Transcatheter mitral valve replacement (TMVR) is an emerging technology with the potential to treat patients with severe mitral regurgitation at excessive risk for surgical mitral valve surgery. Multimodality imaging of the mitral valvular complex and surrounding structures will be an important component for patient selection for TMVR. Our aim was to describe and evaluate a systematic multi-slice computed tomography (MSCT) image analysis methodology that provides measurements relevant for transcatheter mitral valve replacement.<br />Methods and Results: A systematic step-by-step measurement methodology is described for structures of the mitral valvular complex including: the mitral valve annulus, left ventricle, left atrium, papillary muscles and left ventricular outflow tract. To evaluate reproducibility, two observers applied this methodology to a retrospective series of 49 cardiac MSCT scans in patients with heart failure and significant mitral regurgitation. For each of 25 geometrical metrics, we evaluated inter-observer difference and intra-class correlation. The inter-observer difference was below 10% and the intra-class correlation was above 0.81 for measurements of critical importance in the sizing of TMVR devices: the mitral valve annulus diameters, area, perimeter, the inter-trigone distance, and the aorto-mitral angle.<br />Conclusions: MSCT can provide measurements that are important for patient selection and sizing of TMVR devices. These measurements have excellent inter-observer reproducibility in patients with functional mitral regurgitation.
- Subjects :
- Aged
Aged, 80 and over
Cardiac Catheterization methods
Female
Heart Valve Prosthesis
Heart Valve Prosthesis Implantation methods
Humans
Male
Middle Aged
Mitral Valve surgery
Multidetector Computed Tomography
Observer Variation
Patient Selection
Prosthesis Design
Reproducibility of Results
Retrospective Studies
Heart Atria diagnostic imaging
Heart Ventricles diagnostic imaging
Mitral Valve diagnostic imaging
Papillary Muscles diagnostic imaging
Ventricular Dysfunction, Left
Subjects
Details
- Language :
- English
- ISSN :
- 1969-6213
- Volume :
- 12
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 26606733
- Full Text :
- https://doi.org/10.4244/EIJY15M11_09