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Five Simultaneous Primary Tumors in a Single Patient: A Case Report and Review of the Literature.

Authors :
Williamson CW
Paravati A
Ghassemi M
Lethert K
Hua P
Hartman P
Sanghvi P
Source :
Case reports in oncology [Case Rep Oncol] 2015 Oct 20; Vol. 8 (3), pp. 432-8. Date of Electronic Publication: 2015 Oct 20 (Print Publication: 2015).
Publication Year :
2015

Abstract

Multiple primary malignancies (MPMs) are present when a patient is diagnosed with more than one primary malignancy and when each tumor is histologically unrelated to the others. MPMs are considered synchronous when they present within 6 months of one another. Here, we report the case of a 57-year-old woman with a past medical history significant for melanoma in 1988, who presented in 2014 with 5 distinct tumors within 4 months: malignant melanoma of the right popliteal fossa, invasive lobular breast carcinoma, diffuse large B cell lymphoma, nodular lymphocyte predominant Hodgkin lymphoma, and a giant cell tumor of tendon sheath/pigmented villonodular synovitis. We discuss her treatment and also present a brief review of the literature. The incidence of MPMs appears to be on the rise, which demands an interdisciplinary, multimodal, and personalized approach to care.

Details

Language :
English
ISSN :
1662-6575
Volume :
8
Issue :
3
Database :
MEDLINE
Journal :
Case reports in oncology
Publication Type :
Report
Accession number :
26600775
Full Text :
https://doi.org/10.1159/000440799