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[AN ANIMAL MODEL OF INTENTIONAL TREMOR].

Authors :
Albertin SV
Source :
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova [Ross Fiziol Zh Im I M Sechenova] 2015 Aug; Vol. 101 (8), pp. 949-57.
Publication Year :
2015

Abstract

The paper describes a model of intentional form of tremor developed in experiments in animals. Experiments with lesion of nucleus caudatus revealed the important role of this structure to regulate normal relationships between activity of reciprocal muscles under producing the non stereotypic forms of motor behavior. The model may be used to study the etiology and pathogenesis of intentional tremor as well as for preclinical testing of pharmacological drugs potentially perspective for correction of given form of diskinesia in humans.

Details

Language :
Russian
ISSN :
0869-8139
Volume :
101
Issue :
8
Database :
MEDLINE
Journal :
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova
Publication Type :
Academic Journal
Accession number :
26591590