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Cushing Disease Presenting as Primary Psychiatric Illness: A Case Report and Literature Review.
- Source :
-
Journal of psychiatric practice [J Psychiatr Pract] 2015 Nov; Vol. 21 (6), pp. 449-57. - Publication Year :
- 2015
-
Abstract
- We report the case of a woman with long-standing refractory depression and psychotic features who was eventually diagnosed with Cushing disease. After surgical treatment of a pituitary adenoma, she experienced gradual psychiatric recovery and was eventually able to discontinue all psychotropic medication. We review the psychiatric components of Cushing disease, implications of psychiatric illnesses for the treatment and prognosis of Cushing disease, and potential pathophysiological mechanisms linking glucocorticoid excess to psychiatric illness.
- Subjects :
- Female
Humans
Middle Aged
Psychiatric Status Rating Scales
Treatment Outcome
Adenoma surgery
Affective Disorders, Psychotic diagnosis
Affective Disorders, Psychotic etiology
Affective Disorders, Psychotic physiopathology
Affective Disorders, Psychotic therapy
Hypophysectomy methods
Pituitary ACTH Hypersecretion complications
Pituitary ACTH Hypersecretion diagnosis
Pituitary ACTH Hypersecretion psychology
Pituitary ACTH Hypersecretion surgery
Pituitary Neoplasms surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1538-1145
- Volume :
- 21
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Journal of psychiatric practice
- Publication Type :
- Academic Journal
- Accession number :
- 26554329
- Full Text :
- https://doi.org/10.1097/PRA.0000000000000113