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Cancer treatment in determination of hearing loss.
- Source :
-
Brazilian journal of otorhinolaryngology [Braz J Otorhinolaryngol] 2016 Jan-Feb; Vol. 82 (1), pp. 65-9. Date of Electronic Publication: 2015 Oct 17. - Publication Year :
- 2016
-
Abstract
- Introduction: Chemotherapy and radiotherapy in oncology have repercussions in hearing health, and can damage structures of the inner ear. These repercussions usually, result in a bilateral and irreversible hearing loss.<br />Objective: To identify sensorineural hearing loss cases with complaints of tinnitus and difficulty in speech understanding and investigate their relationship with the types of chemotherapy and radiotherapy the patients received.<br />Methods: Cross-sectional, clinical, observational, analytical, historical cohort study of 58 subjects treated in a public hospital in the state of Sergipe, diagnosed with neoplasia. The subjects were submitted to anamnesis, conventional pure tone audiometry, and speech recognition threshold.<br />Results: Of the 116 ears, 25.9% presented sensorioneural hearing loss characterized by changes in high frequencies. There was a positive correlation between hearing loss and the association of chemotherapy and radiotherapy (p=0.035; R=0.196). The auditory complaint analysis shows that most of the subjects had tinnitus and speech understanding difficulty, even with a normal auditory threshold.<br />Conclusions: Cancer treatment causes hearing loss, associated with the administration of chemotherapy and radiotherapy. Cyclophosphamide increased the risk of causing hearing loss. Complaints of tinnitus and speech understanding difficulty were observed.<br /> (Copyright © 2015 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.)
- Subjects :
- Adult
Audiometry, Pure-Tone
Auditory Threshold
Brazil
Cohort Studies
Cross-Sectional Studies
Ear, Inner drug effects
Ear, Inner radiation effects
Female
Humans
Male
Middle Aged
Neoplasms drug therapy
Neoplasms radiotherapy
Tinnitus chemically induced
Antineoplastic Agents adverse effects
Hearing Loss, Sensorineural etiology
Radiotherapy adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1808-8686
- Volume :
- 82
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Brazilian journal of otorhinolaryngology
- Publication Type :
- Academic Journal
- Accession number :
- 26549572
- Full Text :
- https://doi.org/10.1016/j.bjorl.2014.12.010