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Cancer treatment in determination of hearing loss.

Authors :
Oliveira PF
Oliveira CS
Andrade JS
Santos TF
Oliveira-Barreto AC
Source :
Brazilian journal of otorhinolaryngology [Braz J Otorhinolaryngol] 2016 Jan-Feb; Vol. 82 (1), pp. 65-9. Date of Electronic Publication: 2015 Oct 17.
Publication Year :
2016

Abstract

Introduction: Chemotherapy and radiotherapy in oncology have repercussions in hearing health, and can damage structures of the inner ear. These repercussions usually, result in a bilateral and irreversible hearing loss.<br />Objective: To identify sensorineural hearing loss cases with complaints of tinnitus and difficulty in speech understanding and investigate their relationship with the types of chemotherapy and radiotherapy the patients received.<br />Methods: Cross-sectional, clinical, observational, analytical, historical cohort study of 58 subjects treated in a public hospital in the state of Sergipe, diagnosed with neoplasia. The subjects were submitted to anamnesis, conventional pure tone audiometry, and speech recognition threshold.<br />Results: Of the 116 ears, 25.9% presented sensorioneural hearing loss characterized by changes in high frequencies. There was a positive correlation between hearing loss and the association of chemotherapy and radiotherapy (p=0.035; R=0.196). The auditory complaint analysis shows that most of the subjects had tinnitus and speech understanding difficulty, even with a normal auditory threshold.<br />Conclusions: Cancer treatment causes hearing loss, associated with the administration of chemotherapy and radiotherapy. Cyclophosphamide increased the risk of causing hearing loss. Complaints of tinnitus and speech understanding difficulty were observed.<br /> (Copyright © 2015 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.)

Details

Language :
English
ISSN :
1808-8686
Volume :
82
Issue :
1
Database :
MEDLINE
Journal :
Brazilian journal of otorhinolaryngology
Publication Type :
Academic Journal
Accession number :
26549572
Full Text :
https://doi.org/10.1016/j.bjorl.2014.12.010