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Surgical and Medical Treatment of Pyloric and Duodenal Pythiosis in a Dog.
- Source :
-
Journal of the American Animal Hospital Association [J Am Anim Hosp Assoc] 2015 Nov-Dec; Vol. 51 (6), pp. 385-91. - Publication Year :
- 2015
-
Abstract
- A 5 yr old, male, neutered mixed-breed dog was referred for persistent vomiting 2 wk following a pyloric biopsy for a pyloric outflow obstruction. Histopathology at the time of initial surgery was suggestive of pythiosis. Following referral, the dog underwent radical surgical treatment with a Billroth II procedure, partial pancreatectomy, and cholecystoduodenostomy. Histopathology and serology confirmed the diagnosis of pythiosis and medical treatment consisting of itraconazole and terbinafine was started postoperatively. Serology titers were checked again at 8, 12, and 24 wk postoperatively revealing a positive response to treatment and no reoccurrence of pythiosis. Since surgery, the patient experienced waxing and waning elevations of liver values and laparoscopic liver biopsies 10 mo postoperatively revealed hepatic cirrhosis with fibrosis, bile duct hyperplasia, and chronic inflammation. This report documents successful treatment of pyloric/duodenal pythiosis and the long-term (17 mo) consequences associated with the Billroth II, partial pancreatectomy, and biliary rerouting in the dog.
- Subjects :
- Animals
Antifungal Agents therapeutic use
Dietary Supplements
Dog Diseases pathology
Dogs
Duodenal Diseases drug therapy
Duodenal Diseases pathology
Duodenal Diseases surgery
Gastrointestinal Agents therapeutic use
Itraconazole therapeutic use
Male
Naphthalenes therapeutic use
Pancrelipase therapeutic use
Pylorus pathology
Stomach Diseases drug therapy
Stomach Diseases pathology
Stomach Diseases surgery
Terbinafine
Dog Diseases therapy
Duodenal Diseases veterinary
Pythiosis therapy
Stomach Diseases veterinary
Subjects
Details
- Language :
- English
- ISSN :
- 0587-2871
- Volume :
- 51
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Journal of the American Animal Hospital Association
- Publication Type :
- Academic Journal
- Accession number :
- 26535457
- Full Text :
- https://doi.org/10.5326/JAAHA-MS-6217