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Severe Acute Anemia After Liver Transplantation in an Elderly Jehovah's Witness Treated With High-dose Erythropoietin and Ferric Carboxymaltose: A Case Report.
Severe Acute Anemia After Liver Transplantation in an Elderly Jehovah's Witness Treated With High-dose Erythropoietin and Ferric Carboxymaltose: A Case Report.
- Source :
-
Transplantation proceedings [Transplant Proc] 2015 Oct; Vol. 47 (8), pp. 2548-51. - Publication Year :
- 2015
-
Abstract
- Background: There is no standard treatment for patients with severe anemia who refuse blood transfusion or cannot receive red blood cells.<br />Case Report: After an orthotopic liver transplantation, an elderly Jehovah's Witness who refused blood transfusion presented with severe acute anemia with hemorrhagic shock. The calculated red blood cell loss was near 70%. Associated with surgical treatment and supportive measures, the patient was treated with high-dose erythropoietin and ferric carboxymaltose.<br />Results: The patient presented a rapid increase in hemoglobin concentration and reticulocyte count with resolution of hemorrhagic shock after the proposed pharmacologic treatment combined with local hemostatic measures. She was transferred to a low-risk unit 4 days after transplantation and was discharged from the hospital on day 10. The hemoglobin concentration was normal 35 days after the bleeding event.<br />Conclusion: This case demonstrated that a protocol with high-dose erythropoietin and ferric carboxymaltose may be an option for patients with severe anemia who refuse blood transfusion or cannot receive red blood cells.<br /> (Copyright © 2015 Elsevier Inc. All rights reserved.)
- Subjects :
- Anemia etiology
Blood Transfusion statistics & numerical data
Female
Humans
Maltose therapeutic use
Middle Aged
Reticulocyte Count
Shock, Hemorrhagic drug therapy
Shock, Hemorrhagic etiology
Treatment Outcome
Treatment Refusal
Anemia drug therapy
Erythropoietin administration & dosage
Ferric Compounds therapeutic use
Jehovah's Witnesses
Liver Transplantation adverse effects
Maltose analogs & derivatives
Subjects
Details
- Language :
- English
- ISSN :
- 1873-2623
- Volume :
- 47
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Transplantation proceedings
- Publication Type :
- Academic Journal
- Accession number :
- 26518969
- Full Text :
- https://doi.org/10.1016/j.transproceed.2015.09.014