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[Co-activation of AMPK and mTORC1: a therapeutic application of synthetic lethality in acute myeloid leukemia].
- Source :
-
Medecine sciences : M/S [Med Sci (Paris)] 2015 Oct; Vol. 31 (10), pp. 836-9. Date of Electronic Publication: 2015 Oct 19. - Publication Year :
- 2015
- Subjects :
- Animals
Autophagy drug effects
Cell Death drug effects
Humans
Imidazoles therapeutic use
Leukemia, Myeloid, Acute metabolism
Mechanistic Target of Rapamycin Complex 1
Mice
Pyrimidinones therapeutic use
Sirolimus therapeutic use
TOR Serine-Threonine Kinases
AMP-Activated Protein Kinases metabolism
Leukemia, Myeloid, Acute pathology
Leukemia, Myeloid, Acute therapy
Molecular Targeted Therapy methods
Multiprotein Complexes agonists
Subjects
Details
- Language :
- French
- ISSN :
- 1958-5381
- Volume :
- 31
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Medecine sciences : M/S
- Publication Type :
- Periodical
- Accession number :
- 26481022
- Full Text :
- https://doi.org/10.1051/medsci/20153110009