Dark Blood Magnetic Resonance Lymphangiography Using Dual-Agent Relaxivity Contrast (DARC-MRL): A Novel Method Combining Gadolinium and Iron Contrast Agents.

Authors :: Maki JH
Neligan PC
Briller N
Mitsumori LM
Wilson GJ
Source :: Current problems in diagnostic radiology [Curr Probl Diagn Radiol] 2016 May-Jun; Vol. 45 (3), pp. 174-9. Date of Electronic Publication: 2015 Aug 11.
Publication Year :: 2016
Abstract: The objective of this study was to develop and demonstrate a technique to eliminate venous enhancement in contrast-enhanced magnetic resonance lymphangiography through shortening T2(⁎) in the blood pool, thus allowing for a lymphatic-only map. Administration of the blood-pool iron agent ferumoxtyol in addition to intracutaneous gadolinium during contrast-enhanced magnetic resonance lymphangiography allows for suppression of vascular structures to achieve venous-free lymphatic mapping.<br /> (Copyright © 2015 Mosby, Inc. All rights reserved.)

Subjects :: Blood diagnostic imaging
Humans
Lymphography methods
Phantoms, Imaging
Contrast Media
Ferrosoferric Oxide
Gadolinium DTPA
Image Enhancement methods
Lymphedema diagnostic imaging
Magnetic Resonance Imaging methods

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