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Transplantation of Tissue-Engineered Cartilage in an Animal Model (Xenograft and Autograft): Construct Validation.
- Source :
-
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2015; Vol. 1340, pp. 247-59. - Publication Year :
- 2015
-
Abstract
- Tissue engineering holds great promise for cartilage repair with minimal donor-site morbidity. The in vivo maturation of a tissue-engineered construct can be tested in the subcutaneous tissues of the same species for autografts or of immunocompromised animals for allografts or xenografts. This section describes detailed protocols for the surgical transplantation of a tissue-engineered construct into an animal model to assess construct validity.
- Subjects :
- Animals
Autografts
Cartilage cytology
Cartilage immunology
Cartilage metabolism
Chondrocytes immunology
Chondrocytes metabolism
Graft Rejection immunology
Graft Rejection prevention & control
Graft Survival
Heterografts
Immunocompromised Host
Mice, Nude
Models, Animal
Rabbits
Time Factors
Cartilage transplantation
Chondrocytes transplantation
Implants, Experimental adverse effects
Regenerative Medicine methods
Tissue Engineering methods
Subjects
Details
- Language :
- English
- ISSN :
- 1940-6029
- Volume :
- 1340
- Database :
- MEDLINE
- Journal :
- Methods in molecular biology (Clifton, N.J.)
- Publication Type :
- Academic Journal
- Accession number :
- 26445844
- Full Text :
- https://doi.org/10.1007/978-1-4939-2938-2_18