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Regenerative medicine: Hepatic progenitor cells up their game in the therapeutic stakes.
- Source :
-
Nature reviews. Gastroenterology & hepatology [Nat Rev Gastroenterol Hepatol] 2015 Nov; Vol. 12 (11), pp. 610-1. Date of Electronic Publication: 2015 Oct 06. - Publication Year :
- 2015
-
Abstract
- Bipotential hepatic progenitor cells (HPCs) are recognized as making modest contributions to hepatocyte regeneration, though never credited with major liver repopulation. A new study in mice demonstrates HPCs can make a massive contribution to hepatocyte replacement, suggesting HPCs have the potential to be an effective cell therapy for liver failure.
Details
- Language :
- English
- ISSN :
- 1759-5053
- Volume :
- 12
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Nature reviews. Gastroenterology & hepatology
- Publication Type :
- Periodical
- Accession number :
- 26441248
- Full Text :
- https://doi.org/10.1038/nrgastro.2015.168