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Postapplication Fipronil Exposure Following Use on Pets.
- Source :
-
Journal of toxicology and environmental health. Part A [J Toxicol Environ Health A] 2015; Vol. 78 (19), pp. 1217-26. Date of Electronic Publication: 2015 Oct 05. - Publication Year :
- 2015
-
Abstract
- Fipronil is a pyrazole acaricide and insecticide that may be used for insect, tick, lice, and mite control on pets. Residents' short-term and long-term postapplication exposures to fipronil, including secondary environmental exposures, were estimated using data from chemical-specific studies. Estimations of acute (24-h) absorbed doses for residents were based on U.S. Environmental Protection Agency (U.S. EPA) 2012 standard operating procedures (SOPs) for postapplication exposure. Chronic exposures were not estimated for residential use, as continuous, long-term application activities were unlikely to occur. Estimated acute postapplication absorbed doses were as high as 0.56 μg/kg-d for toddlers (1-2 yr) in households with treated pets based on current U.S. EPA SOPs. Acute toddler exposures estimated here were fivefold larger in comparison to adults. Secondary exposure from the household environment in which a treated pet lives that is not from contacting the pet, but from contacting the house interior to which pet residues were transferred, was estimated based on monitoring socks worn by pet owners. These secondary exposures were more than an order of magnitude lower than those estimated from contacting the pet and thus may be considered negligible.
- Subjects :
- Administration, Cutaneous
Administration, Oral
Adult
Animals
Cats
Child, Preschool
Dogs
Environmental Exposure statistics & numerical data
Family Characteristics
Female
Humans
Infant
Insecticides administration & dosage
Male
Pesticide Residues adverse effects
Pyrazoles administration & dosage
Environmental Exposure adverse effects
Insecticides adverse effects
Pets
Pyrazoles adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1528-7394
- Volume :
- 78
- Issue :
- 19
- Database :
- MEDLINE
- Journal :
- Journal of toxicology and environmental health. Part A
- Publication Type :
- Academic Journal
- Accession number :
- 26437174
- Full Text :
- https://doi.org/10.1080/15287394.2015.1076363