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Comparison of aortic root anatomy and calcification distribution between Asian and Caucasian patients who underwent transcatheter aortic valve implantation.
- Source :
-
The American journal of cardiology [Am J Cardiol] 2015 Nov 15; Vol. 116 (10), pp. 1566-73. Date of Electronic Publication: 2015 Aug 31. - Publication Year :
- 2015
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Abstract
- The current transcatheter aortic valve implantation (TAVI) devices have been designed to fit Caucasian and Latin American aortic root anatomies. We evaluated the racial differences in aortic root anatomy and calcium distribution in patients with aortic stenosis who underwent TAVI. We conducted a multicenter study of 4 centers in Asia and Europe, which includes consecutive patients who underwent TAVI with preprocedural multidetector computed tomography. Quantitative assessment of aortic root dimensions, calcium volume for leaflet, and left ventricular outflow tract were retrospectively performed in a centralized core laboratory. A total of 308 patients (Asian group, n = 202; Caucasian group, n = 106) were analyzed. Compared to Caucasian group, Asian group had smaller annulus area (406.3 ± 69.8 vs 430.0 ± 76.8 mm(2); p = 0.007) and left coronary cusp diameter (30.2 ± 3.2 vs 31.1 ± 3.4 mm; p = 0.02) and lower height of left coronary artery ostia (12.0 ± 2.5 vs 13.4 ± 3.4 mm; p <0.001). Of baseline anatomic characteristics, body height showed the highest correlation with annulus area (Pearson correlation r = 0.64; p <0.001). Co-existence of lower height of left coronary artery ostia (<12 mm) and small diameter of left coronary cusp (<30 mm) were more frequent in Asian group compared with Caucasian group (35.6% vs 20.8%; p = 0.02). In contrast, there were no differences in calcium volumes of leaflet (367.2 ± 322.5 vs 359.1 ± 325.7 mm(3); p = 0.84) and left ventricular outflow tract (8.9 ± 23.4 vs 10.1 ± 23.8 mm(3); p = 0.66) between 2 groups. In conclusion, judicious consideration will be required to perform TAVI for short patients with lower height of left coronary artery ostia and small sinus of Valsalva.<br /> (Copyright © 2015 Elsevier Inc. All rights reserved.)
- Subjects :
- Aged, 80 and over
Aortic Valve surgery
Aortic Valve Stenosis diagnostic imaging
Aortic Valve Stenosis etiology
Asia epidemiology
Calcinosis diagnostic imaging
Calcinosis epidemiology
Cardiac Catheterization
Europe epidemiology
Female
Humans
Incidence
Male
Aorta, Thoracic diagnostic imaging
Aortic Valve diagnostic imaging
Aortic Valve Stenosis surgery
Calcinosis complications
Multidetector Computed Tomography methods
Transcatheter Aortic Valve Replacement
Subjects
Details
- Language :
- English
- ISSN :
- 1879-1913
- Volume :
- 116
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- The American journal of cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 26428022
- Full Text :
- https://doi.org/10.1016/j.amjcard.2015.08.021