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Review of topical beta blockers as treatment for infantile hemangiomas.
- Source :
-
Survey of ophthalmology [Surv Ophthalmol] 2016 Jan-Feb; Vol. 61 (1), pp. 51-8. Date of Electronic Publication: 2015 Sep 25. - Publication Year :
- 2016
-
Abstract
- The treatment of infantile hemangiomas changed from the use of oral corticosteroids to oral propranolol on the serendipitous discovery of propanolol's clinical effectiveness in 2008. Since then, clinicians have begun to use topical beta blockers--in particular, timolol maleate 0.5% gel forming solution--with good effect. Topical beta blockers are now used for lesions with both deep and superficial components and those that are amblyogenic. When initiated in the proliferative phase of the lesion, the effectiveness of the treatment can be seen within days. There is no consensus on dosing, treatment bioavailability, or clinical assessment of lesions, but these are topics for future research.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)
- Subjects :
- Administration, Topical
Adrenergic beta-Antagonists administration & dosage
Humans
Ophthalmic Solutions
Propranolol administration & dosage
Propranolol therapeutic use
Timolol administration & dosage
Timolol therapeutic use
Adrenergic beta-Antagonists therapeutic use
Hemangioma, Capillary drug therapy
Neoplastic Syndromes, Hereditary drug therapy
Retinal Neoplasms drug therapy
Skin Neoplasms drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1879-3304
- Volume :
- 61
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Survey of ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 26408055
- Full Text :
- https://doi.org/10.1016/j.survophthal.2015.08.006