Back to Search
Start Over
A novel actor in antitumoral immunity: The thymus-specific serine protease TSSP/PRSS16 involved in CD4 + T-cell maturation.
- Source :
-
Oncoimmunology [Oncoimmunology] 2015 Apr 02; Vol. 4 (9), pp. e1026536. Date of Electronic Publication: 2015 Apr 02 (Print Publication: 2015). - Publication Year :
- 2015
-
Abstract
- The maturation of a specific subset of CD4 <superscript>+</superscript> T lymphocytes in the thymus is dependent on cortical thymic epithelial cells expressing the protease thymus-specific serine protease (TSSP, also known as PRSS16). Recently, we unveiled the involvement of TSSP in tumor suppression through its effect on the CD4 <superscript>+</superscript> T compartment.
Details
- Language :
- English
- ISSN :
- 2162-4011
- Volume :
- 4
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Oncoimmunology
- Publication Type :
- Academic Journal
- Accession number :
- 26405595
- Full Text :
- https://doi.org/10.1080/2162402X.2015.1026536