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[CEREBRAL MICROGLIA AND MICROGLIAL MARKERS].

Authors :
Korzhevskiy DE
Kirik OV
Source :
Morfologiia (Saint Petersburg, Russia) [Morfologiia] 2015; Vol. 147 (3), pp. 37-44.
Publication Year :
2015

Abstract

In recent years, there has been a steady increase of interest in various aspects of the organization and functioning of microglia. However, the information on modern immunocytochemical methods of its identification is ambiguous and requires systematization. In the present paper. the main attention is focused on microglial markers--the proteins (Iba-1, CD11b, CD68, HLA-DR, and some others) expressed by normal microgliocytes and those activated by the effects of damaging factors. Characterization of markers and methods of microglia immunocytochemical labeling is combined with an analysis of the data concerning the origin and structural organization of microgliocytes.

Details

Language :
Russian
ISSN :
1026-3543
Volume :
147
Issue :
3
Database :
MEDLINE
Journal :
Morfologiia (Saint Petersburg, Russia)
Publication Type :
Academic Journal
Accession number :
26390545