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[CEREBRAL MICROGLIA AND MICROGLIAL MARKERS].
- Source :
-
Morfologiia (Saint Petersburg, Russia) [Morfologiia] 2015; Vol. 147 (3), pp. 37-44. - Publication Year :
- 2015
-
Abstract
- In recent years, there has been a steady increase of interest in various aspects of the organization and functioning of microglia. However, the information on modern immunocytochemical methods of its identification is ambiguous and requires systematization. In the present paper. the main attention is focused on microglial markers--the proteins (Iba-1, CD11b, CD68, HLA-DR, and some others) expressed by normal microgliocytes and those activated by the effects of damaging factors. Characterization of markers and methods of microglia immunocytochemical labeling is combined with an analysis of the data concerning the origin and structural organization of microgliocytes.
- Subjects :
- Animals
Biomarkers metabolism
CD11b Antigen metabolism
Humans
Microglia cytology
Microglia metabolism
Rats
Antigens, CD metabolism
Antigens, Differentiation, Myelomonocytic metabolism
Calcium-Binding Proteins metabolism
HLA-DR Antigens metabolism
Microfilament Proteins metabolism
Microglia physiology
Subjects
Details
- Language :
- Russian
- ISSN :
- 1026-3543
- Volume :
- 147
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Morfologiia (Saint Petersburg, Russia)
- Publication Type :
- Academic Journal
- Accession number :
- 26390545