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Jubanines F-J, cyclopeptide alkaloids from the roots of Ziziphus jujuba.
- Source :
-
Phytochemistry [Phytochemistry] 2015 Nov; Vol. 119, pp. 90-5. Date of Electronic Publication: 2015 Sep 08. - Publication Year :
- 2015
-
Abstract
- Five Ib-type cyclopeptide alkaloids, jubanines F-J (1-5), and three known compounds, nummularine B (6), daechuine-S3 (7), and mucronine K (8) were isolated from the roots of Ziziphus jujuba. Their structures were fully characterized by spectroscopic analyses in combination with chemical derivatization. Compounds 1-3, and 6 were evaluated for their antiviral activity against the porcine epidemic diarrhea virus (PEDV). Compounds 2, 3, and 6 showed potent inhibitory effects on PEDV replication.<br /> (Copyright © 2015 Elsevier Ltd. All rights reserved.)
- Subjects :
- Alkaloids chemistry
Alkaloids pharmacology
Antiviral Agents chemistry
Antiviral Agents pharmacology
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Peptides, Cyclic chemistry
Peptides, Cyclic pharmacology
Plant Roots chemistry
Porcine epidemic diarrhea virus drug effects
Republic of Korea
Alkaloids isolation & purification
Antiviral Agents isolation & purification
Peptides, Cyclic isolation & purification
Ziziphus chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1873-3700
- Volume :
- 119
- Database :
- MEDLINE
- Journal :
- Phytochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 26361730
- Full Text :
- https://doi.org/10.1016/j.phytochem.2015.09.001