Effect of remote ischemic postconditioning in inflammatory changes of the lung parenchyma of rats submitted to ischemia and reperfusion.

Authors :: Dorsa RC
Pontes JC
Antoniolli AC
Silva GV
Benfatti RA
Santos CH
Pontes ER
Goldiano JA
Source :: Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular [Rev Bras Cir Cardiovasc] 2015 Jul-Sep; Vol. 30 (3), pp. 353-9.
Publication Year :: 2015
Abstract: Objective: To assess the effects of postconditioning remote in ischemia-reperfusion injury in rat lungs.<br />Methods: Wistar rats (n=24) divided into 3 groups: GA (I/R) n=8, GB (R-Po) n=8, CG (control) n=8, underwent ischemia for 30 minutes artery occlusion abdominal aorta, followed by reperfusion for 60 minutes. Resected lungs and performed histological analysis and classification of morphological findings in accordance with the degree of tissue injury. Statistical analysis of the mean rating of the degree of tissue injury.<br />Results: GA (3.6), GB (1.3) and CG (1.0). (GA GB X P<0.05).<br />Conclusion: The remote postconditioning was able to minimize the inflammatory lesion of the lung parenchyma of rats undergoing ischemia and reperfusion process.

Subjects :: Animals
Ischemia therapy
Lung pathology
Male
Pneumonia prevention & control
Random Allocation
Rats, Wistar
Reperfusion Injury pathology
Reproducibility of Results
Severity of Illness Index
Time Factors
Treatment Outcome
Ischemic Postconditioning methods
Lung blood supply
Reperfusion Injury prevention & control

Language :: English
Volume :: 30
Issue :: 3
Database :: MEDLINE
Journal :: Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular
Publication Type :: Academic Journal
Accession number :: 26313726
Full Text :: https://doi.org/10.5935/1678-9741.20150005

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