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Congenital Malformations Associated With a Single Umbilical Artery in Twin Pregnancies.

Authors :
Mitchell SE
Reidy K
Da Silva Costa F
Palma-Dias R
Cade TJ
Umstad MP
Source :
Twin research and human genetics : the official journal of the International Society for Twin Studies [Twin Res Hum Genet] 2015 Oct; Vol. 18 (5), pp. 595-600. Date of Electronic Publication: 2015 Aug 20.
Publication Year :
2015

Abstract

A single umbilical artery (SUA) was identified in 1.5% of twin pregnancies. The presence of a SUA in a twin pregnancy was associated with a 50% incidence of fetal anomalies, many of them complex and severe. The embryology and pathophysiological mechanisms associated with a SUA are reviewed. Aneuploidy is relatively common and should be considered, particularly in the presence of associated anomalies. Fetal growth restriction is frequent and preterm delivery is common.

Details

Language :
English
ISSN :
1832-4274
Volume :
18
Issue :
5
Database :
MEDLINE
Journal :
Twin research and human genetics : the official journal of the International Society for Twin Studies
Publication Type :
Academic Journal
Accession number :
26289035
Full Text :
https://doi.org/10.1017/thg.2015.59