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[Organ preserving strategies for rectal cancer treatment].

Authors :
Vendrely V
Denost Q
Amestoy F
Célérier B
Smith D
Rullier A
Rullier É
Source :
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique [Cancer Radiother] 2015 Oct; Vol. 19 (6-7), pp. 404-9. Date of Electronic Publication: 2015 Aug 13.
Publication Year :
2015

Abstract

For rectal cancers, the current standard of care consists of chemoradiation followed by radical surgery with total mesorectal excision. Oncologic results are good, especially regarding local recurrence rates, but at the cost of high morbidity rates and poor anorectal, urinary and sexual function results. Since chemoradiation yields 15 to 25% pathological complete response, the role of radical surgery is questioned for patients presenting with good response after chemoradiation and two organ preservation strategies have been offered: watch and wait strategy and local excision strategy. The aim of this review is to give the results of organ preservation after chemoradiotherapy series and to highlight different questions regarding initial patient's selection, complete clinical response definition, risk of mesorectal nodal involvement, follow-up modalities as well as oncologic and functional results.<br /> (Copyright © 2015 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved.)

Details

Language :
French
ISSN :
1769-6658
Volume :
19
Issue :
6-7
Database :
MEDLINE
Journal :
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Publication Type :
Academic Journal
Accession number :
26278990
Full Text :
https://doi.org/10.1016/j.canrad.2015.05.009