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Adolescent pregnancy; a determinant of bone mineral density in peri-menopausal women?
- Source :
-
Maturitas [Maturitas] 2015 Oct; Vol. 82 (2), pp. 203-7. Date of Electronic Publication: 2015 Jul 23. - Publication Year :
- 2015
-
Abstract
- Objective: The present study aims to determine the effects of a history of adolescent pregnancy (AP) on the bone mineral density (BMD) of perimenopausal women.<br />Methods: Overall, 240 women aged between 40 and 55 years, with a complaint of oligomenorrhea or amenorrhea not exceeding 1 year in duration, were evaluated. Evaluation included a DEXA scan and a detailed demographic survey for bone health. Comparison was made between women with a history of AP and those without.<br />Results: In total, 87 women who had a history of AP were compared with 153 women who did not have a history of AP. The study groups did not differ significantly for most of the evaluated demographic factors. Women with a history of AP had higher gravidity and parity. Comparison of T-scores revealed lumbar BMD to be unaffected by AP (P=0.184), whereas femoral BMD was positively influenced by a history of AP (0.78±0.65 vs -1.06±0.67; P=0.042). In covariance regression models, after adjusting for parity and age of first menarche, AP still positively influenced femoral BMD. Without a history of AP, women were at increased risk for osteoporosis of femoral neck (odds ratio, 2.8, 95% CI 1.75-4.8).<br />Conclusions: The effects of AP on BMD are not well elucidated. Women with a history of AP had better femoral BMD scores, indicating a possible protective influence of AP on bone health.<br />Brief Summary: Pregnancy during adolescence is associated with a better femoral bone mineral density than pregnancy at an older age. However, the effects did not extend to lumbar spine bone mineral density.<br /> (Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1873-4111
- Volume :
- 82
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Maturitas
- Publication Type :
- Academic Journal
- Accession number :
- 26276102
- Full Text :
- https://doi.org/10.1016/j.maturitas.2015.07.007