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Diffusion-weighted MR imaging using FASE sequence for 3T MR system: Preliminary comparison of capability for N-stage assessment by means of diffusion-weighted MR imaging using EPI sequence, STIR FASE imaging and FDG PET/CT for non-small cell lung cancer patients.
- Source :
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European journal of radiology [Eur J Radiol] 2015 Nov; Vol. 84 (11), pp. 2321-31. Date of Electronic Publication: 2015 Jul 26. - Publication Year :
- 2015
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Abstract
- Purpose: To prospectively compare the diagnostic capability of diffusion-weighted MR imaging obtained with fast advantage spin-echo sequence (FASE-DWI) and echo planar imaging sequence (EPI-DWI), short inversion time inversion recovery fast advanced spin-echo (STIR FASE) imaging and FDG PET/CT for N-stage assessment of non-small cell carcinoma (NSCLC) patients.<br />Materials and Methods: 95 consecutive operable NSCLC patients underwent STIR FASE imaging, FASE-DWI and EPI-DWI with a 3T system, integrated PET/CT, surgical treatment and pathological and follow-up examinations. Probability of lymph node metastasis was visually assessed using a 5-point visual scoring system. ROC analyses were used to compare diagnostic capability of all methods, while their diagnostic performance was also compared by means of McNemar's test on a per node basis. Finally, McNemar's test was also used for statistical comparison of accuracy of N-stage assessment.<br />Results: Areas under the curve (Azs) for STIR FASE imaging (Az=0.95) and FASE-DWI (Az=0.92) were significantly larger than those for EPI-DWI (Az=0.78; p<0.0001 for STIR FSE imaging and FASE-DWI) and PET/CT (Az=0.85; p=0.0001 for STIR FSE imaging, p=0.03 for FASE-DWI) on a per node basis analysis. Accuracy of N-stage assessment using STIR FASE imaging (84.2% [80/95]) and FASE-DWI (83.2% [79/95]) was significantly higher than that using EPI-DWI (76.8% [73/95]; p=0.02 for STIR FASE imaging, p=0.03 for FASE-DWI) and PET/CT (73.7% [70/95]; p=0.002 for STIR FSE imaging, p=0.004 for FASE-DWI).<br />Conclusion: Qualitative N-stage assessments of NSCLC patients obtained with FASE-DWI as well as STIR FASE imaging are more sensitive and/or accurate than those obtained with EPI-DWI and FDG PET/CT.<br /> (Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.)
- Subjects :
- Aged
Aged, 80 and over
Diffusion Magnetic Resonance Imaging instrumentation
Female
Humans
Lung diagnostic imaging
Lung pathology
Male
Middle Aged
Multimodal Imaging methods
Prospective Studies
ROC Curve
Radiopharmaceuticals
Reproducibility of Results
Sensitivity and Specificity
Carcinoma, Non-Small-Cell Lung diagnosis
Diffusion Magnetic Resonance Imaging methods
Echo-Planar Imaging methods
Fluorodeoxyglucose F18
Lung Neoplasms diagnosis
Positron-Emission Tomography methods
Tomography, X-Ray Computed methods
Subjects
Details
- Language :
- English
- ISSN :
- 1872-7727
- Volume :
- 84
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- European journal of radiology
- Publication Type :
- Academic Journal
- Accession number :
- 26231045
- Full Text :
- https://doi.org/10.1016/j.ejrad.2015.07.019