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Changes in filtering bleb morphology after bleb-related infection.
- Source :
-
Japanese journal of ophthalmology [Jpn J Ophthalmol] 2015 Sep; Vol. 59 (5), pp. 312-7. Date of Electronic Publication: 2015 Jul 30. - Publication Year :
- 2015
-
Abstract
- Purpose: To verify, by use of data collected by the Japan Glaucoma Society Survey of Bleb-related Infection (JGSSBI), that bleb morphology changes within 12 months of the development of bleb-related infection.<br />Methods: JGSSBI data from 57 eyes of 57 patients with primary open-angle glaucoma and normal tension glaucoma who developed a bleb-related infection were analyzed. Morphological features of the blebs were graded by use of a predetermined grading system. Multiple logistic regression analysis was conducted to identify factors relating to bleb morphology which were associated with poor outcome.<br />Results: Bleb sizes, including both circumferential and tangential lengths, were significantly smaller for stage IIIa/IIIb infections than for stage I/II bleb infections (P = 0.009 and P = 0.026 for the circumferential and tangential lengths, respectively; Fisher's direct probability test). The bleb wall also became significantly thicker during stage IIIa/IIIb infections (P = 0.003). After infection, intraocular pressure (IOP) increased significantly for all cases but was no different in the three subgroups (i.e. stage I, stage II, and stage IIIa/IIIb bleb infections). Multiple logistic regression analysis revealed that a stage III infection was significantly associated with a poor outcome for the bleb.<br />Conclusions: This study revealed that the filtering bleb became smaller, both tangentially and circumferentially, and thicker, after stage III infections than after stage I or II infections.
- Subjects :
- Anti-Bacterial Agents therapeutic use
Female
Glaucoma, Open-Angle physiopathology
Humans
Intraocular Pressure physiology
Low Tension Glaucoma physiopathology
Male
Eye Infections, Bacterial microbiology
Glaucoma, Open-Angle surgery
Low Tension Glaucoma surgery
Surgical Wound Infection microbiology
Surgically-Created Structures pathology
Trabeculectomy
Subjects
Details
- Language :
- English
- ISSN :
- 1613-2246
- Volume :
- 59
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Japanese journal of ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 26220820
- Full Text :
- https://doi.org/10.1007/s10384-015-0398-9