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Diagnostic accuracy of late iodine enhancement on cardiac computed tomography with a denoise filter for the evaluation of myocardial infarction.
- Source :
-
The international journal of cardiovascular imaging [Int J Cardiovasc Imaging] 2015 Dec; Vol. 31 Suppl 2, pp. 177-85. Date of Electronic Publication: 2015 Jul 23. - Publication Year :
- 2015
-
Abstract
- We evaluated the image quality and diagnostic performance of late iodine enhancement (LIE) in dual-source computed tomography (DSCT) with low kilo-voltage peak (kVp) images and a denoise filter for the detection of acute myocardial infarction (AMI) in comparison with late gadolinium enhancement (LGE) magnetic resonance imaging (MRI). The Hospital Ethics Committee approved the study protocol. Before discharge, 19 patients who received percutaneous coronary intervention after AMI underwent DSCT and 1.5 T MRI. Immediately after coronary computed tomography (CT) angiography, contrast medium was administered at a slow injection rate. LIE-CT scans were acquired via dual-energy CT and reconstructed as 100-, 140-kVp, and mixed images. An iterative three-dimensional edge-preserved smoothing filter was applied to the 100-kVp images to obtain denoised 100-kVp images. The mixed, 140-kVp, 100-kVp, and denoised 100-kVp images were assessed using contrast-to-noise ratio (CNR), and their diagnostic performance in comparison with MRI and infarcted volumes were evaluated. Three hundred four segments of 19 patients were evaluated. Fifty-three segments showed LGE in MRI. The median CNR of the mixed, 140-, 100-kVp and denoised 100-kVp images was 3.49, 1.21, 3.57, and 6.08, respectively. The median CNR was significantly higher in the denoised 100-kVp images than in the other three images (P < 0.05). The denoised 100-kVp images showed the highest diagnostic accuracy and sensitivity. The percentage of myocardium in the four CT image types was significantly correlated with the respective MRI findings. The use of a denoise filter with a low-kVp image can improve CNR, sensitivity, and accuracy in LIE-CT.
- Subjects :
- Aged
Aged, 80 and over
Equipment Design
Female
Humans
Male
Middle Aged
Predictive Value of Tests
Prospective Studies
Reproducibility of Results
Tissue Survival
Contrast Media administration & dosage
Gadolinium DTPA administration & dosage
Iopamidol administration & dosage
Magnetic Resonance Imaging
Myocardial Infarction diagnostic imaging
Myocardial Infarction pathology
Myocardium pathology
Radiographic Image Interpretation, Computer-Assisted methods
Tomography, X-Ray Computed methods
Subjects
Details
- Language :
- English
- ISSN :
- 1875-8312
- Volume :
- 31 Suppl 2
- Database :
- MEDLINE
- Journal :
- The international journal of cardiovascular imaging
- Publication Type :
- Academic Journal
- Accession number :
- 26202159
- Full Text :
- https://doi.org/10.1007/s10554-015-0716-9