Outbreak of Colistin-Resistant, Carbapenemase-Producing Klebsiella pneumoniae: Are We at the End of the Road?

Authors :: van Duin D
Doi Y
Source :: Journal of clinical microbiology [J Clin Microbiol] 2015 Oct; Vol. 53 (10), pp. 3116-7. Date of Electronic Publication: 2015 Jul 22.
Publication Year :: 2015
Abstract: Carbapenem-resistant Klebsiella pneumoniae strains that produce K. pneumoniae carbapenemase (KPC) have spread globally in the last decade. Colistin is a key agent in treating infections caused by this pathogen. In this issue of the Journal of Clinical Microbiology, Giani et al. (T. Giani, F. Arena, G. Vaggelli, V. Conte, A Chiarell, L. H. De Angelis, R. Fornaini, M. Grazzini, F. Niccolini, P. Pecile, and G. M. Rossolini, J Clin Microbiol 53:3341-3344, 2015, http://dx.doi.org/10.1128/JCM.01017-15) describe a sustained outbreak of colistin-resistant KPC-producing K. pneumoniae.<br /> (Copyright © 2015, American Society for Microbiology. All Rights Reserved.)

Subjects :: Humans
Anti-Bacterial Agents pharmacology
Bacterial Proteins metabolism
Colistin pharmacology
Disease Outbreaks
Drug Resistance, Bacterial
Klebsiella Infections epidemiology
Klebsiella pneumoniae isolation & purification
beta-Lactamases metabolism

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