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[Antiviral activity of aqueous extracts of the birch fungus Inonotus obliquus on the human immunodeficiency virus].
- Source :
-
Voprosy virusologii [Vopr Virusol] 2015; Vol. 60 (2), pp. 35-8. - Publication Year :
- 2015
-
Abstract
- Fractions of aqueous and water-alcohol extracts of the birch fungus Inonotus obliquus have antiviral effect against the human immunodeficiency virus type 1 (HIV-1). Antiviral properties of low toxic extracts were manifested in the concentration of 5.0 μg/ml upon simultaneous application with the virus in the lymphoblastoid cells culture MT-4. The extract of the birch fungus can be used for development of new antiviral drugs, inhibitors of HIV-replication when used both in the form of individual drugs and as a part of complex therapy.
- Subjects :
- Anti-HIV Agents chemistry
Cell Line, Tumor
Complex Mixtures chemistry
Ethanol chemistry
HIV Infections metabolism
HIV Infections pathology
Humans
Water chemistry
Anti-HIV Agents pharmacology
Basidiomycota chemistry
Complex Mixtures pharmacology
HIV Infections drug therapy
HIV-1 physiology
Virus Replication drug effects
Subjects
Details
- Language :
- Russian
- ISSN :
- 0507-4088
- Volume :
- 60
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Voprosy virusologii
- Publication Type :
- Academic Journal
- Accession number :
- 26182655