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[Antiviral activity of aqueous extracts of the birch fungus Inonotus obliquus on the human immunodeficiency virus].

Authors :
Shibnev VA
Garaev TM
Finogenova MP
Kalnina LB
Nosik DN
Source :
Voprosy virusologii [Vopr Virusol] 2015; Vol. 60 (2), pp. 35-8.
Publication Year :
2015

Abstract

Fractions of aqueous and water-alcohol extracts of the birch fungus Inonotus obliquus have antiviral effect against the human immunodeficiency virus type 1 (HIV-1). Antiviral properties of low toxic extracts were manifested in the concentration of 5.0 μg/ml upon simultaneous application with the virus in the lymphoblastoid cells culture MT-4. The extract of the birch fungus can be used for development of new antiviral drugs, inhibitors of HIV-replication when used both in the form of individual drugs and as a part of complex therapy.

Details

Language :
Russian
ISSN :
0507-4088
Volume :
60
Issue :
2
Database :
MEDLINE
Journal :
Voprosy virusologii
Publication Type :
Academic Journal
Accession number :
26182655