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Adaptability to changes in temporal structure is fornix-dependent.
- Source :
-
Learning & memory (Cold Spring Harbor, N.Y.) [Learn Mem] 2015 Jul 15; Vol. 22 (8), pp. 354-9. Date of Electronic Publication: 2015 Jul 15 (Print Publication: 2015). - Publication Year :
- 2015
-
Abstract
- Recognition memory deficits, even after short delays, are sometimes observed following hippocampal damage. One hypothesis links the hippocampus with processes in updating contextual memory representation. Here, we used fornix transection, which partially disconnects the hippocampal system, and compares the performance of fornix-transected monkeys with normal monkeys on two versions of a delayed-matching-to-position task with short delays. Spatial recognition memory was affected by fornix transection only when the temporal structure of the task changed across trials, while differences in motor control, motivation, perception, or short-term memory were not critical. We attributed the deficit to a compromised ability in tracking changes in task temporal structure.<br /> (© 2015 Kwok et al.; Published by Cold Spring Harbor Laboratory Press.)
- Subjects :
- Analysis of Variance
Animals
Fornix, Brain injuries
Macaca fascicularis
Macaca mulatta
Male
Memory, Short-Term physiology
Motivation physiology
Motor Activity physiology
Neuropsychological Tests
Reaction Time
Adaptation, Psychological physiology
Fornix, Brain physiology
Recognition, Psychology physiology
Spatial Memory physiology
Time Perception physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1549-5485
- Volume :
- 22
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Learning & memory (Cold Spring Harbor, N.Y.)
- Publication Type :
- Academic Journal
- Accession number :
- 26179228
- Full Text :
- https://doi.org/10.1101/lm.038851.115