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[Autologous mesenchymal stem cells and cutaneus autograft as a treatment for chronic ulcer secondary to diabetes mellitus 2].
- Source :
-
Cirugia y cirujanos [Cir Cir] 2015 Nov-Dec; Vol. 83 (6), pp. 532-6. Date of Electronic Publication: 2015 Jul 09. - Publication Year :
- 2015
-
Abstract
- Background: Diabetes mellitus 2 has become a global problem. It is estimated that 15% to 25% of patients could develop a chronic ulcer in their life, and nearly 33% of direct care costs of the diabetes mellitus 2 is spent on treating these ulcers. Mesenchymal stem cells have emerged as a promising cell source for the treatment of these ulcers.<br />Clinical Case: The case is presented of a 67 year-old male with a history of diabetes mellitus, acute myocardial infarction, and food ulcer chronic involving right foot and part of his leg. He was treated with mesenchymal stem cell management, resulting in skin graft integration and full coverage of the lesion.<br />Conclusion: The implementation of mesenchymal stem cell techniques for treatment of chronic ulcer is feasible. The impact on the population would lead to a significant improvement in their quality of life and reduce healthcare spending.<br /> (Copyright © 2015 Academia Mexicana de Cirugía A.C. Published by Masson Doyma México S.A. All rights reserved.)
- Subjects :
- Aged
Amputation, Surgical
Anti-Bacterial Agents therapeutic use
Bone Marrow Cells
Debridement
Diabetic Foot etiology
Escherichia coli Infections drug therapy
Escherichia coli Infections etiology
Escherichia coli Infections surgery
Foot Ulcer etiology
Foot Ulcer microbiology
Humans
Leg Ulcer etiology
Leg Ulcer microbiology
Male
Staphylococcal Skin Infections drug therapy
Staphylococcal Skin Infections etiology
Staphylococcal Skin Infections surgery
Tissue and Organ Harvesting methods
Toes surgery
Transplantation, Autologous
Wound Infection etiology
Diabetes Mellitus, Type 2 complications
Diabetic Foot surgery
Foot Ulcer surgery
Leg Ulcer surgery
Mesenchymal Stem Cell Transplantation
Skin Transplantation
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 2444-054X
- Volume :
- 83
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Cirugia y cirujanos
- Publication Type :
- Academic Journal
- Accession number :
- 26164137
- Full Text :
- https://doi.org/10.1016/j.circir.2015.05.036