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Stachybisbins A and B, the first cases of seco-bisabosquals from Stachybotrys bisbyi.

Authors :
Bao YR
Chen GD
Wu YH
Li XX
Hu D
Liu XZ
Li Y
Yao XS
Gao H
Source :
Fitoterapia [Fitoterapia] 2015 Sep; Vol. 105, pp. 151-5. Date of Electronic Publication: 2015 Jul 03.
Publication Year :
2015

Abstract

Stachybisbins A (1) and B (2), two new meroterpenoids with unprecedented seco-bisabosqual skeleton, together with three biogenetically related metabolites (3-5), were isolated from a wetland fungal strain of Stachybotrys bisbyi. The structures of the new compounds were determined by spectroscopic analyses, modified Mosher's method, and quantum chemical CD method. The cytotoxic activities of all compounds were tested against HL-60, SMMC-7721, A-549, MCF-7, and SW480 human cancer cell lines.<br /> (Copyright © 2015. Published by Elsevier B.V.)

Details

Language :
English
ISSN :
1873-6971
Volume :
105
Database :
MEDLINE
Journal :
Fitoterapia
Publication Type :
Academic Journal
Accession number :
26149533
Full Text :
https://doi.org/10.1016/j.fitote.2015.06.022