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Prescribing patterns of antenatal corticosteroids in women with threatened preterm labor.
- Source :
-
European journal of obstetrics, gynecology, and reproductive biology [Eur J Obstet Gynecol Reprod Biol] 2015 Sep; Vol. 192, pp. 47-53. Date of Electronic Publication: 2015 Jun 17. - Publication Year :
- 2015
-
Abstract
- Objective: To assess the impact of cervical length (CL) measurement and fetal fibronectin testing (fFN) on the clinicians' decision to prescribe antenatal corticosteroids (ACS) to women with symptoms of preterm labor.<br />Study Design: This is a secondary analysis of a prospective cohort study including women with symptoms of preterm labor and intact membranes between 24 and 34 weeks' gestation. We compared the proportion prescribed and completed ACS courses, preterm delivery within seven days and median intervals from ACS to delivery in four groups: group 1 CL<10 mm, group 2 CL 10-30 mm and positive fFN, group 3 CL 10-30 mm and negative fFN, group 4 CL>30 mm.<br />Results: ACS were prescribed to 63/65 (97%) women in group 1, 176/192 (91%) in group 2, 111/172 women (65%) in group 3 and 55/242 (23%) in group 4. In group 1, 42 (65%) women delivered within seven days, compared to 34 (18%) in group 2, 6 (3%) in group 3 and 3 (1%) in group 4. Median intervals between ACS and delivery were 6 days (IQR 3-61 days), 44 days (IQR 17-69 days), 53 days (IQR 37-77 days) and 66 days (IQR 43-78 days) in group 1, 2, 3 and 4 respectively.<br />Conclusion: ACS were prescribed frequently to women with a CL of 10-30 mm and a negative fFN test or a CL>30 mm. There is room for improvement in the prescription of ACS in these low risk women.<br /> (Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.)
- Subjects :
- Adult
Drug Prescriptions
Female
Gestational Age
Humans
Pregnancy
Prenatal Care
Prospective Studies
Time Factors
Young Adult
Adrenal Cortex Hormones therapeutic use
Cervical Length Measurement
Fibronectins analysis
Obstetric Labor, Premature drug therapy
Practice Patterns, Physicians'
Premature Birth drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1872-7654
- Volume :
- 192
- Database :
- MEDLINE
- Journal :
- European journal of obstetrics, gynecology, and reproductive biology
- Publication Type :
- Academic Journal
- Accession number :
- 26149479
- Full Text :
- https://doi.org/10.1016/j.ejogrb.2015.06.008