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Piper betle-mediated synthesis, characterization, antibacterial and rat splenocyte cytotoxic effects of copper oxide nanoparticles.
- Source :
-
Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2016 Sep; Vol. 44 (6), pp. 1400-5. Date of Electronic Publication: 2015 Jul 06. - Publication Year :
- 2016
-
Abstract
- The study reports a simple, inexpensive, and eco-friendly synthesis of copper oxide nanoparticles (CuONPs) using Piper betle leaf extract. Formation of CuONPs was confirmed by UV-visible spectroscopy at 280 nm. Transmission electron microscopy (TEM) images showed that the CuONPs were spherical, with an average size of 50-100 nm. The scanning electron microscopy (SEM)-energy dispersive spectroscopy (EDS) peak was observed approximately at 1 and 8 keV. The X-ray diffraction (XRD) studies indicated that the particles were crystalline in nature. CuONPs effectively inhibited the growth of phytopathogens Ralstonia solanacearum and Xanthomonas axonopodis. The cytotoxic effect of the synthesized CuONPs was analyzed using rat splenocytes. The cell viability was decreased to 94% at 300 μg/mL.
- Subjects :
- Animals
Cell Survival drug effects
Cells, Cultured
Rats
Rats, Sprague-Dawley
Spleen cytology
Anti-Bacterial Agents chemical synthesis
Anti-Bacterial Agents chemistry
Anti-Bacterial Agents pharmacology
Copper chemistry
Cytotoxins chemical synthesis
Cytotoxins chemistry
Cytotoxins pharmacology
Nanoparticles chemistry
Piper betle chemistry
Plant Extracts chemistry
Plant Leaves chemistry
Ralstonia solanacearum growth & development
Spleen metabolism
Xanthomonas axonopodis growth & development
Subjects
Details
- Language :
- English
- ISSN :
- 2169-141X
- Volume :
- 44
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Artificial cells, nanomedicine, and biotechnology
- Publication Type :
- Academic Journal
- Accession number :
- 26148178
- Full Text :
- https://doi.org/10.3109/21691401.2015.1029630