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Nuclear β-Catenin under Control.

Authors :
Fagotto F
Source :
Developmental cell [Dev Cell] 2015 Jun 22; Vol. 33 (6), pp. 625-6.
Publication Year :
2015

Abstract

During Wnt stimulation, β-catenin accumulates in the nucleus, where it regulates gene transcription. In this issue of Developmental Cell, Lu et al. (2015) report a mechanism that specifically targets this nuclear pool for degradation, using lysine demethylation as ubiquitination signal.<br /> (Copyright © 2015 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1878-1551
Volume :
33
Issue :
6
Database :
MEDLINE
Journal :
Developmental cell
Publication Type :
Academic Journal
Accession number :
26102597
Full Text :
https://doi.org/10.1016/j.devcel.2015.06.005