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Evaluation of YB-1 levels in patients with endometriosis.
- Source :
-
European journal of obstetrics, gynecology, and reproductive biology [Eur J Obstet Gynecol Reprod Biol] 2015 Aug; Vol. 191, pp. 68-71. Date of Electronic Publication: 2015 Jun 09. - Publication Year :
- 2015
-
Abstract
- Objective: The objective of this study is the evaluation of serum YB-1 levels in the diagnosis of endometriosis.<br />Study Design: Serum samples of 12 patients with histologically confirmed endometriosis and of 10 control patients were collected. Western blot analysis was used to assess serum YB-1 levels. Groups were compared with Student's t-test or, if not normally distributed, with the Mann-Whitney test. Sensitivity and specificity for the potential diagnostic performance of serum YB-1 were assessed by receiver operating characteristic (ROC) curves.<br />Results: Serum YB-1 levels were significantly higher in patients with endometriosis (=0.004). The area under the curve was 0.867 (95% confidence interval 0.714-1.019) with sensitivity and specificity of 83.3% and 70% respectively.<br />Conclusions: Serum YB-1 levels in patients with endometriosis are significantly higher compared to control patients and may be used as a potential diagnostic biomarker for endometriosis.<br /> (Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1872-7654
- Volume :
- 191
- Database :
- MEDLINE
- Journal :
- European journal of obstetrics, gynecology, and reproductive biology
- Publication Type :
- Academic Journal
- Accession number :
- 26093350
- Full Text :
- https://doi.org/10.1016/j.ejogrb.2015.05.008