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[Possibilities of cryopreservation of ovarian tissue for fertility preservation in cancer patients].

Authors :
Gamzatoval ZKh
Komlichenko EV
Kostareva AA
Galagudza MM
Berlev IV
Urmancheeva AF
Ulrikh EA
Malashicheva AB
Belyakova MV
Molotkova MY
Source :
Voprosy onkologii [Vopr Onkol] 2015; Vol. 61 (2), pp. 199-204.
Publication Year :
2015

Abstract

One of the effective methods of fertility preservation is an autologous transplantation of cryopreserved ovarian tissue. Currently, according to the world literature, after orthotopic autotransplantation of ovarian tissue 37 healthy children were born. In 2014 at the North-West Federal Medical Research Center it was established Cryobank of ovarian tissue, which is now kept 50 samples of ovarian tissue of man. Cryoconservation is performed by standard slow freezing. Autotransplantation of cryopreserved ovarian tissue has unique advantages over other methods of fertility preservation. This method does not lead to the postponement of anticancer therapy, safe for hormone-dependent cancer and can be performed regardless of the day of menstrual cycle and it is the only option for fertility preservation in prepubertal girls. The use of this method in clinical practice leads to restoration of endocrine function of the ovaries as well as of fertility in the future.

Details

Language :
Russian
ISSN :
0507-3758
Volume :
61
Issue :
2
Database :
MEDLINE
Journal :
Voprosy onkologii
Publication Type :
Academic Journal
Accession number :
26087598