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Tissue Blood Flow During Remifentanil Infusion With Carbon Dioxide Loading.
- Source :
-
Anesthesia progress [Anesth Prog] 2015 Summer; Vol. 62 (2), pp. 51-6. - Publication Year :
- 2015
-
Abstract
- The aim of this study was to investigate the effect of changes in end-tidal carbon dioxide tension (ETCO2) during remifentanil (Remi) infusion on oral tissue blood flow in rabbits. Eight male tracheotomized Japan White rabbits were anesthetized with sevoflurane under mechanical ventilation. The infusion rate of Remi was 0.4 μg/kg/min. Carbon dioxide was added to the inspired gas to change the inspired CO2 tension to prevent changes in the ventilating condition. Observed variables were systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), common carotid artery blood flow (CCBF), tongue mucosal blood flow (TBF), mandibular bone marrow tissue blood flow (BBF), masseter muscle tissue blood flow (MBF), upper alveolar tissue blood flow (UBF), and lower alveolar tissue blood flow (LBF). The CCBF, TBF, BBF, UBF, and LBF values were increased, while MBF was decreased, under hypercapnia, and vice versa. The BBF, UBF, and LBF values were increased, while the MBF value was decreased, under hypercapnia during Remi infusion, and vice versa. The BBF, MBF, UBF, and LBF values, but not the CCBF and TBF values, changed along with ETCO2 changes during Remi infusion.
- Subjects :
- Alveolar Process blood supply
Animals
Arterial Pressure drug effects
Blood Pressure drug effects
Bone Marrow blood supply
Capnography methods
Carbon Dioxide administration & dosage
Carotid Artery, Common drug effects
Heart Rate drug effects
Male
Mandible blood supply
Masseter Muscle blood supply
Rabbits
Regional Blood Flow drug effects
Remifentanil
Respiration, Artificial methods
Tongue blood supply
Tracheostomy methods
Anesthetics, Intravenous administration & dosage
Hypercapnia physiopathology
Mouth blood supply
Piperidines administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 0003-3006
- Volume :
- 62
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Anesthesia progress
- Publication Type :
- Academic Journal
- Accession number :
- 26061573
- Full Text :
- https://doi.org/10.2344/0003-3006-62.2.51